21-Day Galapagos, Peru & Bolivia Tour: Machu Picchu & Uyuni

Andes & Galapagos Grand Journey

21 days

A Tailor-Made 21-Day South America Journey Across Ecuador, Peru & Bolivia

Jhimy Sante

Presented by Jhimy Sante, Your Local Expert

Experience three of South America's most extraordinary landscapes in one customizable 21-day journey. Begin with a six-day Galapagos experience, continue through Peru from Lima and Cusco to the Sacred Valley and Machu Picchu, then travel south across Lake Titicaca into Bolivia for La Paz and the surreal landscapes of Uyuni and the Altiplano.

This itinerary is designed as a starting point: the number of nights, Galapagos travel style, hotels, activities and pace can all be adapted before the final trip is planned and quoted.

The Galapagos route shown is a representative sample. Depending on your dates and preferences, the journey may use a different yacht and route, or the cruise can be replaced with an island-hopping program.

A Tailor-Made 21-Day South America Journey Across Ecuador, Peru & Bolivia
A Tailor-Made 21-Day South America Journey Across Ecuador, Peru & Bolivia
A Tailor-Made 21-Day South America Journey Across Ecuador, Peru & Bolivia

21-Day Galapagos, Peru & Bolivia Tour Itinerary

Day 1: Guayaquil to Baltra & Santa Cruz Highlands

Fly from Guayaquil to Baltra and begin a representative 6-day / 5-night Galapagos cruise experience. After arrival procedures and embarkation, explore the Santa Cruz Highlands, where lush volcanic landscapes provide opportunities to observe giant tortoises in their natural environment. The exact vessel and final route are selected according to travel dates, availability and traveler preferences.

Day 2: Isabela Island - volcanic landscapes and coastal wildlife

Explore Isabela through a combination of volcanic scenery, coastal habitats and wildlife-rich visitor areas. A representative day may combine the Tintoreras area, Sierra Negra Volcano, wetlands and an interpretation center, with the final program adapted to the confirmed cruise route.

Day 3: Isabela & Fernandina - the wild western islands

Continue into the western Galapagos, using places such as Moreno Point and Espinoza Point as the model for the day. Expect dramatic lava landscapes, marine wildlife and some of the archipelago's most remote scenery, subject to the itinerary operated by the selected vessel.

Day 4: Fernandina & Isabela - marine wildlife and volcanic shores

Spend another day among the western islands, combining guided walks, wildlife observation and opportunities for marine exploration. A representative route may include Espinoza Point and Tagus Cove, while the final visitor sites depend on the confirmed sailing.

Day 5: Santiago Island - wildlife, beaches and snorkeling

Explore another distinctive Galapagos ecosystem with a day inspired by sites such as Egas Port and Chinese Hat. Guided walks and snorkeling reveal volcanic formations, coastal wildlife and the contrast between land and sea.

Day 6: Black Turtle Cove, Baltra & return to Guayaquil

Enjoy a final morning Galapagos experience inspired by Black Turtle Cove before transferring to the airport. Fly back to Guayaquil and overnight on the mainland before continuing south to Peru.

Day 7: Fly to Lima

Fly from Guayaquil to Lima, meet the PWP team and transfer to the hotel.

Day 8: Lima city and culture, evening flight to Cusco

Explore colonial and modern Lima with a private guide, then transfer to the airport for an evening flight to Cusco and hotel check-in.

Day 9: Cultural Cusco City Tour

Explore Qorikancha, the Plaza de Armas and Sacsayhuaman with a private guide at a comfortable pace.

Day 10: Sacred Valley

Visit selected archaeological sites, communities and landscapes, positioning the itinerary comfortably for Machu Picchu.

Day 11: Machu Picchu and return to Cusco

Travel by train and bus for a private guided visit to Machu Picchu, then return by train and private transfer to Cusco the same day.

Day 12: Travel to Puno

Continue to Lake Titicaca by the selected premium train, tourist service or private route.

Day 13: Lake Titicaca

Navigate to selected islands and communities on the Peruvian side.

Day 14: Cross into Bolivia

Travel via Copacabana toward La Paz, with an optional Isla del Sol program when practical.

Day 15: La Paz

Explore the city, markets, viewpoints and cable cars at an altitude-appropriate pace.

Day 16: Early flight to Uyuni and Salar de Uyuni

Take an early flight from La Paz to Uyuni and begin the salt-flat program on arrival, exploring the Salar and principal surrounding sites before an overnight near Uyuni.

Day 17: Altiplano and Laguna Colorada

Continue by private 4x4 through the high-altitude landscapes toward Laguna Colorada, with an overnight in a remote desert lodge or the best available accommodation for the confirmed route.

Day 18: Return to Uyuni / optional deep-south extension

Return toward Uyuni through the Altiplano with scenic stops. Travelers who specifically want the longer remote circuit may add geysers, hot springs and Laguna Verde before the extended drive back to Uyuni.

Day 19: Return to La Paz

Fly from Uyuni to La Paz and overnight.

Day 20: La Paz buffer / flexible day

Keep a full operational buffer before the international departure. Use it as a relaxed or optional local day according to the traveler and confirmed flight plan.

Day 21: Departure from La Paz

Transfer to the airport for the onward journey.

21-Day Galapagos, Peru & Bolivia Tour: Machu Picchu & Uyuni
Added peace of mind! Postpone your trip at no cost up to 20 days prior to departure No change fee with open dates.

Local Operational Flexibility

Added peace of mind! Postpone your trip at no cost up to 20 days prior to departure No change fee with open dates.

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included

  • Twenty nights of accommodation in selected three-star superior / four-star hotels, confirmed Galapagos lodging and best-available remote Bolivia lodging
  • Breakfast at mainland hotels and meals expressly included by the confirmed Galapagos and remote Bolivia suppliers
  • Galapagos transfers, certified naturalist guiding and activities explicitly included by the selected supplier
  • Lima city and culture service on Day 8
  • Cultural Cusco City Tour on Day 9
  • Sacred Valley guided service on Day 10
  • Machu Picchu visit with confirmed train, bus, entrance, private guiding and same-day return transfer to Cusco
  • Selected Cusco-Puno transport service
  • Lake Titicaca program on the Peruvian side
  • Border assistance and confirmed overland transfer into Bolivia
  • La Paz guided city and cable-car experience
  • Base Uyuni 4x4 circuit stated in the final confirmed program
  • Local operational assistance throughout the journey

not included

  • International airfare
  • Domestic and regional airfare, including flights to and from Galapagos and Uyuni, unless specifically included in the final quotation
  • Lunches and dinners unless expressly included
  • Galapagos park, transit or local fees unless expressly included in the final quotation
  • Airport, border, municipal, tourism or other locally payable taxes not included by suppliers
  • Tips
  • Travel or medical insurance
  • Passport, visa or entry-document expenses when applicable
  • Machu Picchu train or service upgrades beyond the selected base option
  • Optional Isla del Sol experience when not included in the confirmed base routing
  • Day 18 deep-south Uyuni extension with geysers, hot springs and Laguna Verde
  • Premium Galapagos vessel, cabin, lodge or private-guide upgrades not included in the selected base program
*** Prices are valid only for 2026 and subject to updates by the end of 2026. Rates may vary depending on the departure date. Contact us for a personalized quote and more information from one of our Travel Advisors.

Why Travel with Peru Wayna Picchu?

Why Travel with Peru Wayna Picchu?

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Choose From 80+ Handpicked Hotels in Peru

Exclusive hospitality, elegance, location, and perfect facilities: these are the standard features of all hotels carefully selected by Peru Wayna Picchu. Explore our list and discover your perfect hotel. If you have a hotel in mind that you don’t see here, just let us know and we can reserve a room for you at any hotel in Peru.

Casa Andina Standard Benavides

Casa Andina Standard Benavides

Pullman Lima Miraflores

Pullman Lima Miraflores

Hilton Lima Miraflores

Hilton Lima Miraflores

Trains

Our best investment: the opinions of our satisfied travelers

The Voyager

The Voyager

Perurail Vistadome Observatory

Perurail Vistadome Observatory

Hiram Bingham a Belmond train

Hiram Bingham a Belmond train

Why Travelers Love Peru Wayna Picchu

Why Travelers Love Peru Wayna Picchu

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